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Rare Sugars, Biochemicals, Biocatalysts, and Custom Bioprocess Solutions

The Midwest Bioprocessing Center

Formed in 2019, The Midwest Bioprocessing Center is dedicated to bringing important new bioprocess technologies to market for human health and nutrition. The Company combines proprietary molecular biology, biocatalysis and fermentation technology to produce important new industrial compounds. MBC offers a growing catalog of products for sale  and carries out custom synthesis for customers and clients in the pharmaceutical and nutritional research space.  In-house production capabilities range from gram to kilogram scale and larger quantities are produced through our manufacturing partners.  Several of our specialities are detailed below.

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The Home of zuCarb™ Research Carbohydrates & Intermediates

  • Monosaccharides and Oligosaccharides.  The proprietary zuCarb™ technology platform allows us to economically make rare sugars, sugar phosphates and activated sugars that have previously been too expensive or unavailable. These products are potential building blocks for new therapeutics and biochemicals for research applications.  The zuCarb™ technology platform also allows us to produce a wide variety of custom oligosaccharides.  Our growing catalog of products include:

    • Rare/L-sugars
    • Phosphorylated sugars
    • Nucleosides and Activated sugars (GDP, UDP, TDP-sugars/deoxysugars)
    • Custom oligosaccharides and glycoconjugates

     

  • MBC is proud to now offer ThermoCat™ biocatalysts for carrying out a variety of synthetic reactions. ThermoCat enzymes have been engineered to be robust, stable, and highly active. They are functional at both moderate and elevated temperatures and are generally more tolerant to the presence of organic solvents. These properties make them ideal in synthetic biocatlaysis applications.

    The first two enzymes being offered include the ThermoCat™ E009 and E020, two esterases for use in chiral resolution reactions. Since 1995, ThermoCat™ esterases have been known for their high performance and enantioselectivity with E009 and E020 being the most popular.

    ThermoCat™ esterases are available in a variety of quantities—in bulk or in convenient R&D sizes. Contact us for more information!

  • Custom Synthesis Specialties

    MBC specializes in making natural and modified glycochemicals. Our proprietary bioprocess solutions use biocatalysis, fermentation and traditional synthetic chemistry to produce glycochemicals that otherwise difficult, complex, or expensive to make.

    Product specialties include:

    • L-sugars
    • Modified monosaccharides
    • Sugar-phosphates
    • Other unusual glycochemicals
    • Custom oligosaccharide synthesis
    • Small molecule glycosylation

  • Custom Oligosaccharide Application Areas

    Oligosaccharides are key components involved in many cellular processes and also serve as attachment sites for bacteria and viruses for entry into the cell.  

    • Therapeutic and Research Oligosaccharides
    • Human Milk Oligosaccharides
    • Anti-infective and Anti-cancer applications
    • Many others

     

    Interested in Glycans and Oligosaccharides for Antiviral Research?  Please contact us and let us know what you are looking for!

Download Our Catalog:MBC Product Catalog

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