Bioprocess Services – Equipment

  • Agilent Prep HPLC – with RID and DAD detection
  • Agilent 1100 HPLC – with DAD detection
  • Shimadzu Prominence HPLC – with UV detection
  • Shimadzu UHPLC with DAD and ELSD detection
  • Perkin Elmer HPLC – with RID detection
  • Agilent 1260 LC/MS (single quad) – with RID and DAD detection
    • Enhanced mass spec capabilities available through Veloxity Labs
  • General Molecular Biology Equipment
    • Electrodialysis Units, transillumination, etc
    • DNA and Protein analysis
    • Various PCR machines
  • Microplate UV/VIS/Fluorometer readers
  • 4X Benchmark Microplate incubation systems with shaking, mixing, and temperature control to over 65°C
  • Opentrons OT-2 robotic liquid handling system

Shake Flasks

  • Environmental chest shakers up to 60°C

Fermentation

  • 6x 2-10L Sartorius (B. Braun) fermentation systems
  • 1x New Brunswick 16L fermenter
  • 1x 100L New Brunswick fermenter (planned installation 2024)

Chemistry

  • BUCHI Flash Chromatography system
  • General chemistry setup including
    • Distillation
    • Reflux
    • Extractions
    • Air-free reactions

Cell Disruption

  • French press
  • Sonication
  • Waring Blender

Enzyme/Biocatalysis

  • General benchtop and 2L bioreactors capable of incubations up to 80°
  • GZ100 and GZ300 Custom membrane reactors.  Capable of running immobilized enzyme reactions incubated at up to 65 C.
  • Mixing/incubation system capable of incubating 12x microplates up to 100°C
  •  

Separations

  • Centrifugation
  • Microfiltration, GE various
  • Ultrafiltration, GE various (Various membranes from 3K to 500K)
  • Nanofiltration, Sterlitech Benchtop (various membranes from 100K-5K

Chromatography

  • Chromatography systems from lab-scale to 25L. (gravity and pressure flow)
    • Ion exchange, Size Exclusion, Affinity, Silica

Evaporation

  • Rotary evaporators up to 20L pilot

Other

  • Standard Crystallization
  • Oven/drying
  • Low temperature lyophilization

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