Midwest Bioprocessing Center Receives NIH Phase I SBIR Award for New Methods to Produce Important Deoxysugars

Media Contacts:

Elena Chaikin, Marketing Manager
echaikin@mwbioprocessing.com

 

Peoria, IL (June 16, 2022) – The Midwest Bioprocessing Center (MBC), a leading producer of bio-based chemicals for human health and nutrition, announced that it has been awarded a $217,000 grant from the National Institutes of Health to develop new technology to produce important deoxysugars for pharmaceutical drug discovery applications.

These specialized sugars are often important structural components of bioactive natural products, such as antibiotics and anticancer therapeutics.  Although they are of increasing interest to drug discovery researchers who want to test the effect of altering sugar substituents on the therapeutics that they are developing, deoxysugars are often difficult or impossible to synthesize using current chemical technologies.

“Our goal in this project is to support researchers that are working on the development of new therapeutics by allowing them to test the effects of different deoxysugars they can’t currently make or buy,” said Dr. Robert Turner, Principal Investigator on the Project. “We think that these important molecules can have a profound effect on developing new anti-infective and anticancer therapeutics.”

The Company plans on selling the resulting deoxysugars as part of its zuCarb™ line of rare and modified sugars for research applications.  In addition to selling products from its growing catalog, MBC also synthesizes custom chemicals and carries out collaborative research using its proprietary technology platform.

Visit the Company’s website to learn about the Midwest Bioprocessing Center www.mwbioprocessing.com or its zuCarb™ line of rare sugars (www.mwbioprocessing.com/zuCarb).  Inquiries can be sent to products@mwbioprocessing.com.

About the Midwest Bioprocessing Center, LLC.

The Midwest Bioprocessing Center is a start-up biotechnology company formed in 2019 to bring important new bio-based technologies to market for human health and nutrition.  The Midwest Bioprocessing Center has facilities to carry out enzyme biocatalysis, fermentation, chemical synthesis, and product purification for its own use and on behalf of its clients.  MBC’s proprietary brands include the zuCarb™ Rare sugar platform, the ThermoCat™ stable biocatalysts, and the iActive FeruliShield™ Feruloyl Glycerides for Personal Care.  The Company’s proprietary enzyme and fermentation technology platform allows production and modification of carbohydrates, glycochemicals, and lipids that would otherwise be impractical or impossible to make.  The Midwest Bioprocessing Center is located in Peoria, IL and housed in the PeoriaNEXT Innovation Center.  For more information please contact:

products@mwbioprocessing.com

801 W Main St

Peoria, IL 61606

Tel: (630) 230-0349

END

Midwest Bioprocessing Center Earns USDA Certified Biobased Product Label for its iActive™ FeruliShield™ Feruloyl Glycerides

Media Contacts: 

Midwest Bioprocessing Center, LLC
Breanne Mason
bmason@mwbioprocessing.com

USDA BioPreferred® Program 
Vernell Thompson 202.720.4145
vernell.thompson@dm.usda.gov

 

Peoria, IL. (March 1, 2022) — Midwest Bioprocessing Center, LLC announced today that it has earned the U.S. Department of Agriculture (USDA) Certified Biobased Product label for two of its iActive Personal Care ingredients. The products, iActive FeruliShield™ Feruloyl Soy Glycerides (FSG-33), and Feruloyl Coconut Glycerides, (FCG-33) and are now able to display a unique USDA label that highlights its percentage of biobased content.

Third-party verification for a product’s biobased content is administered through the USDA BioPreferred Program, an initiative created by the 2002 Farm Bill (and recently reauthorized by the 2018 Farm Bill). One of the goals of the BioPreferred Program is to increase the development, purchase and use of biobased products.

The USDA Certified Biobased Product label displays a product’s biobased content, which is the portion of a product that comes from a renewable source, such as plant, animal, marine, or forestry feedstocks. Utilizing renewable, biobased materials displaces the need for non-renewable petroleum-based chemicals. Biobased products, through petroleum displacement, have played an increasingly important role in reducing greenhouse gas (GHG) emissions that exacerbate global climate change.

Biobased products are cost-comparative, readily available, and perform as well as or better than their conventional counterparts.

“We are excited to have received certification for our iActive ™ products by the USDA BioPreferred Program,” said David Demirjian, Manager and Cofounder of the Midwest Bioprocessing Center.  “The certification helps underscore our commitment to providing sustainable, bio-based products for Personal Care applications.”

“We applaud Midwest Bioprocessing Center, LLC for earning the USDA Certified Biobased Product label,” said Vernell Thompson, USDA BioPreferred Program. “Products from Midwest Bioprocessing Center, LLC are contributing to an ever-expanding marketplace that adds value to renewable agriculture commodities, creates jobs in rural communities, and decreases our reliance on petroleum.”

According to a report that USDA released in July 2019, biobased products contributed $459 billion to the U.S. economy in 2016 (a 17% increase from 2014) and support, directly and indirectly, 4.6 million jobs. The report’s research team estimates the reduction of fossil fuels and associated GHG emissions from biobased products equivalent to approximately 12 million metric tons of carbon dioxide (CO2) prevented as of 2016. The increased production of renewable chemicals and biobased products contributes to the development and expansion of the U.S. bioeconomy – where society looks to agriculture for sustainable sources of fuel, energy, chemicals, and products.

About Midwest Bioprocessing Center, LLC:
The Midwest Bioprocessing Center is a start-up biotechnology company formed in 2019 to bring important new sustainable bio-based technologies to market for human health and nutrition.  MBC’s proprietary brands include the zuCarb™ Rare sugar platform, the ThermoCat™ stable biocatalysts, and the iActive FeruliShield™ Feruloyl Glycerides for Personal Care.  The Company’s proprietary enzyme and fermentation technology platform allows production and modification of carbohydrates, glycochemicals, and lipids that would otherwise be impractical or impossible to make.  The Midwest Bioprocessing Center is located in Peoria, IL and housed in the PeoriaNEXT Innovation Center. The Midwest Bioprocessing Center has facilities to carry out enzyme biocatalysts, fermentation, chemical synthesis, and product purification. For more information on MBC products and services please contacts:  products@mwbioprocessing.com.  Visit our website at www.mwbioprocessing.com.

About the USDA BioPreferred Program and Certified Biobased Product label
The BioPreferred Program is a USDA-led initiative that assists the development and expansion of markets for biobased products. The BioPreferred Program is transforming the marketplace for biobased products through two initiatives: mandatory purchasing requirements for Federal Agencies and Federal contractors and voluntary product certification and labeling.

Biobased products span a diverse range of applications, such as lubricants, cleaning products, chemicals and bioplastics. The USDA Certified Biobased Product label communicates a product’s biobased content. Expressed as a percentage, biobased content is the ratio of non-fossil organic carbon (new organic carbon) to total organic carbon in a product. New organic carbon is derived from recently-created materials. The total organic carbon in a product consists of new organic carbon and old organic carbon that originates from fossil carbon materials, such as petroleum, coal, or natural gas. More than 3,500 products have earned the USDA Certified Biobased Product label. To learn more about the USDA Certified Biobased Product label please visit www.biopreferred.gov, and follow on Twitter at http://twitter.com/BioPreferred.

Midwest Bioprocessing Center Receives $1.87MM NIH Phase II SBIR Award to Develop Glycans for Antiviral Research

Peoria, IL (January 20, 2022) – The Midwest Bioprocessing Center (MBC), a leading producer of bio-based chemicals for human health and nutrition, announced that it has been award a $1.87MM grant from the National Institutes of Health to develop a variety of new monosaccharides, oligosaccharides, and glycans needed for the study of viral glycobiology and development of new antiviral drugs.

Glycobiology, the study of how complex and unusual sugars interact with our body, is important in a number of ways for viral research. Viral spike proteins which bind to our cells are often heavily glycosylated to both avoid recognition by the immune system or to interact with host receptors.   The host receptor proteins are frequently glycosylated as well.

In support of advancements in this important field of research MBC will be making monosaccharides sugars, nucleoside sugars, oligosaccharides, and other glycans developed during the project available for use by outside investigators during the project.

“This technology will support researchers studying viral pathology, analyses of viral binding and interactions with hosts, studies to develop novel antiviral therapeutics and vaccines, and others.”, said Dr. Leila Aminova, Principal Investigator on the Project.

To learn about other products from MBC such as its zuCarb™ line of rare sugars please visit www.mwbioprocessing.com or email products@mwbioprocessing.com.

 

About the Midwest Bioprocessing Center, LLC.

The Midwest Bioprocessing Center is a start-up biotechnology company formed in 2019 to bring important new bio-based technologies to market for human health and nutrition.  MBC’s proprietary brands include the zuCarb™ Rare sugar platform, the ThermoCat™ stable biocatalysts, and the iActive FeruliShield™ Feruloyl Glycerides for Personal Care.  The Company’s proprietary enzyme and fermentation technology platform allows production and modification of carbohydrates, glycochemicals, and lipids that would otherwise be impractical or impossible to make.  The Midwest Bioprocessing Center is located in Peoria, IL and housed in the PeoriaNEXT Innovation Center. The Midwest Bioprocessing Center has facilities to carry out enzyme biocatalysts, fermentation, chemical synthesis, and product purification. For more information please contact:

products@mwbioprocessing.com

801 W Main St

Peoria, IL 61606

Tel: (630) 230-0349

 

END

The Midwest Bioprocessing Center Announces Acquisition of iActive Naturals Clean Health and Beauty Ingredient Platform

Peoria, IL (March 25, 2021) – The Midwest Bioprocessing Center (MBC), a leading producer of bio-based chemicals for human health and nutrition, announced today that it has acquired the technology, product line and production assets of iActive™ Naturals from the Biotechnology Research and Development Corporation (BRDC).

Products currently include FSG33 and FCG33, two oil-based ferulates derived from soybean oil and coconut oil respectively.  These natural products combine the unique cosmetic properties of ferulic acid, with the ease of formulation of lipids.

“FSG33 and FCG33 are highly effective at providing broad spectrum UV absorption protection and antioxidant activity.  They help bring anti-wrinkling and antiaging properties to lotions and other cosmetic health and beauty products,” said Dr. David Demirjian, Manager and co-founder of the Midwest Bioprocessing Center.  “They can also be an effective SPF booster when used in sunscreens.”

The patented enzyme-based production technology for the iActive products was originally invented at the US Department of Agriculture, Agricultural Research Service, National Center for Agricultural Utilization Research located in Peoria, IL.  Its development was funded in part by the Biotechnology Research and Development Corporation.

“We are excited that the Midwest Bioprocessing Center will be commercializing this technology,” said Dr. Grant Brewen, President of the BRDC.  “Their bioprocess expertise make them an ideal partner for taking these innovative products to their next stage of growth.”

MBC plans on making FSG33 and FCG33 immediately available for commercial sale and is working on additions to the product line including a hemp oil-based product.

For ordering, information, and samples of iActive FSG33 or FCG33, or to learn about other products from MBC such as its zuCarb™ line of rare sugars email products@mwbioprocessing.com.

 

About the USDA, Agricultural Research Service, National Center for Agricultural Research Center (NCAUR).

The focus of the Renewable Products Technology Research Unit at the NCAUR (Peoria, IL) is to develop new technologies for converting renewable agricultural materials into high value chemicals, enzymes, and polymers.  Researchers in the unit use a variety of chemical, microbial, biochemical, and genetic approaches to address the need for new sustainable and environmentally acceptable value-added products.

 

About the Biotechnology Research and Development Corporation

The Biotechnology Research and Development Corporation is a biocollaborative organization dedicated to improving the United States technical competitiveness by commercializing scientific discoveries made in participating government and university agricultural laboratories.

 

About the Midwest Bioprocessing Center, LLC.

The Midwest Bioprocessing Center is a start-up biotechnology company formed in 2019 to bring important new bio-based technologies to market for human health and nutrition.  MBC’s proprietary brands include the zuCarb™ Rare sugar platform, the ThermoCat™ stable biocatalysts, and the iActive ferulated lipids and oils.  The Company’s proprietary technology platform allows production and modification of carbohydrates, glycochemicals, and lipids that would otherwise be impractical or impossible to make.  The Midwest Bioprocessing Center is located in Peoria, IL and housed in the PeoriaNEXT Innovation Center. The Midwest Bioprocessing Center has facilities to carry out enzyme biocatalyisis, fermentation, chemical synthesis, and product purification; and can produce gram to kilogram scale quantities in-house. For more information please contact:

products@mwbioprocessing.com

801 W Main St

Peoria, IL 61606

Tel: (630) 230-0349

The Midwest Bioprocessing Center Announces Phase I SBIR Funding from the NIH to Synthesize Deoxysugars

Peoria, IL (September 1, 2020) – The Midwest Bioprocessing Center (MBC), a leading producer of unique carbohydrates for human health and nutrition, announced today that it has received a $183,138 Phase I Small Business Innovative Research (SBIR) grant from the National Institutes of Health in support of its project entitled “Engineering Methylotrophic Yeast for in vivo Production of Deoxysugars from DHAP”.  

The goal of the project is to develop new ways to synthesize hard-to-make deoxysugars, an important class of carbohydrates useful in the discovery of new pharmaceuticals, production of nutritional products, and other applications.  For example, some deoxy-sugars are natural components of the most commercially successful antibiotics and are key in their antimicrobial activity. Unfortunately, only a small number of deoxy-sugars are commercially available.  More are needed to help develop novel antibiotics which can help treat antibiotic resistant pathogens.  The deoxy-sugar l-fucose is also a key potential building block for many antiviral drugs and in the production of Human Milk Oligosaccharides used in infant formula.

This is a very important but largely underdeveloped area of research” said Dr. Leila Aminova, the Principal Investigator on the Project and MBC’s Director of Product Development.  “The technology we are developing will allow dozens of new deoxy-sugars to be made available to researchers exploring the development of new and improved antibiotics.” 

The new deoxysugars will ultimately be available as part of the Company’s zuCarb™ rare sugar catalog and will also be used internally for the development of new pharmaceuticals and nutritional products being developed at MBC.   For more information on zuCarb™ rare sugars or partnering opportunities please visit www.mwbioprocessing.com or contact the Company at products@mwbioprocessing.com.

 

About Midwest Bioprocessing Center, LLC.

The Midwest Bioprocessing Company is a start-up biotechnology company formed in 2019 to bring important new technologies to market for human health and nutrition.  MBC’s proprietary technology includes the zuCarb™ Rare sugar platform which allows the production and modification of carbohydrates and glycochemicals that would otherwise be impractical or impossible to make.  By expanding the number of sugar building blocks and components that are available to the marketplace—many of which are currently not available or prohibitively expensive—together with the synthetic tools to utilize these new sugars in human health and nutrition applications, the Midwest Bioprocessing Center enables both the discovery of breakthrough drugs as well as the cost-effective commercial production of many glycochemicals.  The Midwest Bioprocessing Center is located in Peoria, IL and housed in the PeoriaNEXT Innovation Center. The Midwest Bioprocessing Center has facilities to carry out enzyme biocatalyisis, fermentation, chemical synthesis, and product purification; and can produce gram to kilogram scale quantities in-house. For more information please contact:

David Demirjian

products@mwbioprocessing.com

801 W Main St

Peoria, IL 61606

Tel: (630) 230-0349

 

END

The Midwest Bioprocessing Center Announces Acquisition of zuCarb™ Rare Sugars Technology

Peoria, IL (July 27, 2019) – The Midwest Bioprocessing Center (MBC), a leading producer of unique carbohydrates for human health and nutrition, announced today that it has acquired the zuCarb™ Rare Sugars technology platform from zuChem Inc.  Founded in 2003, zuChem’s long-term mission was to develop novel carbohydrate technology for a variety of food and pharmaceutical applications.  This included the development of its zuCarb™ technology platform to produce rare sugars, activated sugars, and technology for glycodiversification of small molecules, proteins, and oligosaccharides. zuChem has now focused its commercial efforts and resources on the launch of its commercial xylitol program and transferred the zuCarb™ technology platform to the Midwest Bioprocessing Center.

Much of the technology was initially developed by Leila Aminova, Ph.D. and her colleagues who joined MBC from zuChem.  “I am excited to be continuing the work we began at zuChem” said Dr. Aminova . “Access to this technology gives us dozens of products we can immediately start providing to pharmaceutical and academic researchers for drug discovery and glycobiology.  It also allows us to carry out custom synthesis of sugars and glycoconjugates for a variety of applications”

For more information on zuCarb™ rare sugars please visit the Company’s website at www.mwbioprocessing.com.

 

About Midwest Bioprocessing Center, LLC.

The Midwest Bioprocessing Center is a start-up biotechnology company formed in 2019 to bring important new technologies to market for human health and nutrition.  MBC’s proprietary technology includes the zuCarb™ Rare sugar platform which allows the production and modification of carbohydrates and glycochemicals that would otherwise be impractical or impossible to make.  By expanding the number of sugar building blocks and components that are available to the marketplace—many of which are currently not available or prohibitively expensive—together with the synthetic tools to utilize these new sugars in human health and nutrition applications, the Midwest Bioprocessing Center enables both the discovery of breakthrough drugs as well as the cost-effective commercial production of many glycochemicals.  The Midwest Bioprocessing Center is located in Peoria, IL and housed in the PeoriaNEXT Innovation Center. The Midwest Bioprocessing Center has facilities to carry out enzyme biocatalyisis, fermentation, chemical synthesis, and product purification; and can produce gram to kilogram scale quantities in-house. For more information please contact:

 

David Demirjian

products@mwbioprocessing.com

801 W Main St

Peoria, IL 61606

Midwest Bioprocessing Center Opens Research Labs at the PeoriaNEXT Innovation Center

Peoria, IL (June 30, 2019) – The Midwest Bioprocessing Center (MBC), a leading developer of bioprocess technologies for human health and nutrition, announced today the opening of its research operations at the PeoriaNEXT Innovation Center in Peoria, IL.

“We are excited to locate our Company at the PeoriaNEXT Innovation Center,” said Dr. David Demirjian, Manager and co-founder of MBC.  “The facility provides us with state-of-the art laboratory space to help us fulfill our mission to provide new bioprocess solutions to customers and partners”

The MBC labs house the Company’s molecular biology, biocatalysis and fermentation capabilities and allow the production of novel compounds from gram to kilogram scale using MBC’s proprietary technologies.  MBC will commercialize products through both catalog sales and custom synthesis for customers and clients in the pharmaceutical and nutritional research space.

For more information on MBC technology and custom bioprocess solutions visit the Company’s website at www.mwbioprocessing.com. 

 

About Midwest Bioprocessing Center, LLC.

The Midwest Bioprocessing Center is a start-up biotechnology company formed in 2019 to bring important new technologies to market for human health and nutrition.  The Midwest Bioprocessing Center is located in Peoria, IL and housed in the PeoriaNEXT Innovation Center. The Midwest Bioprocessing Center has facilities to carry out enzyme biocatalyisis, fermentation, chemical synthesis, and product purification; and can produce gram to kilogram scale quantities in-house. For more information please contact:

 

David Demirjian

products@mwbioprocessing.com

801 W Main St

Peoria, IL 61606

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